Modelling of the activation of G-protein coupled receptors: drug free constitutive receptor activity

DOI10.1007/s00285-009-0268-5zbMath1311.92097OpenAlexW2064112127WikidataQ51734154 ScholiaQ51734154MaRDI QIDQ2340015

Yanyan Li

Publication date: 15 April 2015

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-009-0268-5

zbMATH Keywords

asymptotic analysismathematical modellingG-protein coupled receptors

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40)

Related Items (5)

Mathematical modelling of signalling in a two-ligand G-protein coupled receptor system: agonist-antagonist competition ⋮ Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor ⋮ Insights into the dynamics of ligand-induced dimerisation via mathematical modelling and analysis ⋮ Modelling the activation of G-protein coupled receptors by a single drug ⋮ Ligand binding dynamics for pre-dimerised G protein-coupled receptor homodimers: linear models and analytical solutions

Cites Work

• Modelling of signalling via G-protein coupled receptors: pathway-dependent agonist potency and efficacy
• Modelling the activation of G-protein coupled receptors by a single drug
• A theoretical approach to \(G\)-protein modulation of cellular responsiveness
• Unnamed Item

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