Mathematical modelling of p53 basal dynamics and DNA damage response

DOI10.1016/J.MBS.2014.10.010zbMath1315.92026OpenAlexW1992629803WikidataQ42469047 ScholiaQ42469047MaRDI QIDQ2343796

Ket Hing Chong, Sandhya Samarasinghe, Don Kulasiri

Publication date: 6 May 2015

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2014.10.010

zbMATH Keywords

mathematical modelsDNA damage responsep53 basal dynamicsp53 oscillationsp53 pulsatile dynamicsspontaneous pulses

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40)

Related Items (3)

Mathematical modelling of core regulatory mechanism in p53 protein that activates apoptotic switch ⋮ Modeling hepatitis C virus protein and p53 interactions in hepatocytes: implications for carcinogenesis ⋮ P53-Mdm2 Loop Stability and Oscillatory Dynamics with Mdm2-Induced Delay Effect in P53

Uses Software

• DDE-BIFTOOL

Cites Work

• Gene circuit designs for noisy excitable dynamics
• Cell Polarity: Quantitative Modeling as a Tool in Cell Biology
• Numerical bifurcation analysis of delay differential equations using DDE-BIFTOOL

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