A multi-functional analyzer uses parameter constraints to improve the efficiency of model-based gene-set analysis

DOI10.1214/14-AOAS777zbMath1454.62417arXiv1310.6322OpenAlexW3104929327MaRDI QIDQ2349566

Qiuling He, Michael A. Newton, Zhishi Wang, Bret Larget

Publication date: 17 June 2015

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1310.6322

zbMATH Keywords

Bayesian analysisinteger linear programminggene-set enrichment

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Related Items (1)

Single-index modulated multiple testing

Uses Software

• R
• Bioconductor
• KEGG
• Reactome

Cites Work

• A model-based analysis to infer the functional content of a gene list
• Poisson approximation and the Chen-Stein method. With comments and a rejoinder by the authors
• A statistical framework for testing functional categories in microarray data

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