Dynamic optimization of metabolic networks coupled with gene expression

DOI10.1016/j.jtbi.2014.10.035zbMath1314.92059arXiv1309.4936OpenAlexW2072447727WikidataQ46806462 ScholiaQ46806462MaRDI QIDQ2351384

Diego A. Oyarzún, Alexander Bockmayr, Steffen Waldherr

Publication date: 23 June 2015

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1309.4936

zbMATH Keywords

bacterial growthconstraint-based methodsflux optimizationmetabolic-genetic networks

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Genetics and epigenetics (92D10) Systems biology, networks (92C42)

Related Items (7)

Qualitative Behavior of a Metabolic Pathway with Hybrid Feedback ⋮ Regulatory dynamic enzyme-cost flux balance analysis: a unifying framework for constraint-based modeling ⋮ The steady-state assumption in oscillating and growing systems ⋮ Turnpike property in optimal microbial metabolite production ⋮ The promise of dawn: microalgae photoacclimation as an optimal control problem of resource allocation ⋮ Dynamic metabolic resource allocation based on the maximum entropy principle ⋮ Optimal control of bacterial growth for the maximization of metabolite production

Cites Work

• A unified framework for the numerical solution of optimal control problems using pseudospectral methods
• Cell design in bacteria as a convex optimization problem
• Sequential activation of metabolic pathways: a dynamic optimization approach
• A collocation method for optimal control of linear systems with inequality constraints
• Computational cell biology
• Sequence-based analysis of metabolic demands for protein synthesis in prokaryotes
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