The dual role of autoimmune regulator in maintaining normal expression level of tissue-restricted autoantigen in the thymus: a modeling investigation

DOI10.1016/J.MBS.2016.10.002zbMath1377.92023OpenAlexW2538898075WikidataQ50562460 ScholiaQ50562460MaRDI QIDQ2407279

Massimo Pietropaolo, Anmar Khadra, Tina M. Mitre

Publication date: 29 September 2017

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc5392448

zbMATH Keywords

mathematical modelbistable switchT-cell avidityautoimmune regulatorthymic negative selectiontissue-restricted antigens

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Physiology (general) (92C30)

Cites Work

• Modeling transcriptional control in gene networks -- methods, recent results, and future directions
• The role of low avidity T cells in the protection against type 1 diabetes: a modeling investigation
• Modeling Cyclic Waves of Circulating T Cells in Autoimmune Diabetes

This page was built for publication: The dual role of autoimmune regulator in maintaining normal expression level of tissue-restricted autoantigen in the thymus: a modeling investigation