Computing optimal properties of drugs using mathematical models of single channel dynamics
From MaRDI portal
Publication:2415216
DOI10.1515/cmb-2018-0004zbMath1412.92140OpenAlexW3016939841MaRDI QIDQ2415216
Aslak Tveito, Mary M. Maleckar, Glenn Terje Lines
Publication date: 21 May 2019
Published in: Computational and Mathematical Biophysics (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1515/cmb-2018-0004
PDEs in connection with biology, chemistry and other natural sciences (35Q92) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Stochastic partial differential equations (aspects of stochastic analysis) (60H15)
Related Items (3)
On complex dynamics in a Purkinje and a ventricular cardiac cell model ⋮ Combination of multi-variable quadratic adaptive algorithm and hybrid operator splitting method for stability against acceleration in the Markov model of sodium ion channels in the ventricular cell model ⋮ Bifurcation Analysis of a Modified Cardiac Cell Model
Uses Software
Cites Work
- Unnamed Item
- Unnamed Item
- Unnamed Item
- MCMC for hidden Markov models incorporating aggregation of states and filtering
- Computing characterizations of drugs for ion channels and receptors using Markov models
- Computing rates of Markov models of voltage-gated ion channels by inverting partial differential equations governing the probability density functions of the conducting and non-conducting states
- A note on a method for determining advantageous properties of an anti-arrhythmic drug based on a mathematical model of cardiac cells
- A population density approach that facilitates large-scale modeling of neural networks: Analysis and an application in orientation tuning
- Computational cell biology
- Markov chain Monte Carlo fitting of single-channel data from inositol trisphosphate receptors
- An operator splitting method for solving the bidomain equations coupled to a volume conductor model for the torso
- Defining candidate drug characteristics for Long-QT (LQT3) syndrome
- The effect of residual \(\operatorname{Ca}^{2 +}\) on the stochastic gating of \(\operatorname{Ca}^{2 +} \)-regulated \(\operatorname{Ca}^{2 +}\) channel models
- The dynamics of luminal depletion and the stochastic gating of \(\operatorname{Ca}^{2 +} \)-activated \(\operatorname{Ca}^{2 +}\) channels and release sites
- Stochastic processes in cell biology
- Mathematical physiology. I: Cellular physiology
- Elements of Scientific Computing
- On the accuracy of operator splitting for the monodomain model of electrophysiology
- Finite Volume Methods for Hyperbolic Problems
- HOW ANTIARRHYTHMIC DRUGS INCREASE THE RATE OF SUDDEN CARDIAC DEATH
This page was built for publication: Computing optimal properties of drugs using mathematical models of single channel dynamics
