Metabolic impact assessment for heterologous protein production in \textit{Streptomyces lividans} based on genome-scale metabolic network modeling

DOI10.1016/j.mbs.2013.08.006zbMath1281.92025OpenAlexW2086029405WikidataQ44639252 ScholiaQ44639252MaRDI QIDQ2439177

Pieter-Jan D'Huys, Jozef Anné, Ivan Lule, Lieve Van Mellaert, Kristel Bernaerts, Jan F. Van Impe

Publication date: 7 March 2014

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2013.08.006

zbMATH Keywords

(geometric) flux balance analysisgenome-scale metabolic networkheterologous proteinsmouse tumor necrosis factor (mtnf-\(\alpha\))

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

Uses Software

• COBRA Toolbox

Cites Work

• Flux balance analysis: a geometric perspective
• Capturing the essence of a metabolic network: a flux balance analysis approach
• Thermodynamic constraints for biochemical networks

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