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Development and validation of biomarker classifiers for treatment selection

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Publication:2475718
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DOI10.1016/J.JSPI.2007.06.010zbMath1138.62359OpenAlexW2098184866WikidataQ36591860 ScholiaQ36591860MaRDI QIDQ2475718

Richard M. Simon

Publication date: 11 March 2008

Published in: Journal of Statistical Planning and Inference (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc2344143


zbMATH Keywords

DNA microarrayvalidationgenomicspharmacogenomicsclinical trial design


Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)


Related Items (2)

The use of covariates and random effects in evaluating predictive biomarkers under a potential outcome framework ⋮ A signature enrichment design with Bayesian adaptive randomization




Cites Work

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  • Sample size planning for developing classifiers using high-dimensional DNA microarray data
  • Comparison of Discrimination Methods for the Classification of Tumors Using Gene Expression Data
  • Sample size determination in microarray experiments for class comparison and prognostic classification




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