Group up-and-down designs for dose-finding

DOI10.1016/j.jspi.2005.08.002zbMath1089.62132OpenAlexW2075757568MaRDI QIDQ2492509

Misrak Gezmu, Nancy Flournoy

Publication date: 9 June 2006

Published in: Journal of Statistical Planning and Inference (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jspi.2005.08.002

zbMATH Keywords

Markov chainsrandom walksbirth and death processesadaptive designsclinical trialsapplied probabilityphase I clinical trialstoxicity studiesstationary treatment distribution

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05) Estimation in survival analysis and censored data (62N02)

Related Items

Sequential design for binary dose-response experiments ⋮ A new design of the continual reassessment method ⋮ Adaptive clinical trial designs for phase I cancer studies ⋮ Cumulative cohort design for dose-finding ⋮ Approximate cost-efficient sequential designs for binary response models with application to switching measurements ⋮ A two-stage hybrid procedure for estimating an inverse regression function ⋮ Randomized group up and down experiments ⋮ Bayesian hierarchical random-effects meta-analysis and design of phase I clinical trials ⋮ A sequential design for maximizing the probability of a favourable response

Cites Work

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