A quantitative model of error accumulation during PCR amplification

DOI10.1016/J.COMPBIOLCHEM.2005.11.002zbMath1102.92026DBLPjournals/candc/PienaarTNV06OpenAlexW2127476843WikidataQ34984902 ScholiaQ34984902MaRDI QIDQ2500355

Michael Nelson, M. Theron, Hendrik J. Viljoen, Elsje Pienaar

Publication date: 23 August 2006

Published in: Computational Biology and Chemistry (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc1544370

zbMATH Keywords

Polymerase chain reactionCytosine deaminationDepurinationThermal damage

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40) Biophysics (92C05)

Cites Work

• Principles of rapid polymerase chain reactions: mathematical modeling and experimental verification
• A macroscopic kinetic model for DNA polymerase elongation and high-fidelity nucleotide selection

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