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Modelling of signalling via G-protein coupled receptors: pathway-dependent agonist potency and efficacy

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Publication:253454
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DOI10.1016/S0092-8240(03)00055-7zbMath1334.92130OpenAlexW2054156011WikidataQ52011120 ScholiaQ52011120MaRDI QIDQ253454

F. Blanchet-Sadri, M. Dambrine

Publication date: 8 March 2016

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/s0092-8240(03)00055-7


zbMATH Keywords

effector pathwaysG-proteinpathway-dependent agonistspatial heterogeneity


Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Cell biology (92C37)


Related Items (5)

Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor ⋮ Modeling and genetic algorithm optimization of early events in signal transduction via dynamics of G-protein-coupled receptors: Internalization consideration ⋮ A simple reaction kinetic model of rapid (G protein dependent) and slow (\(\beta\)-Arrestin dependent) transmission ⋮ Modelling the effect of caveolae on G-protein activation ⋮ Modelling of the activation of G-protein coupled receptors: drug free constitutive receptor activity







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