Model-based selection of the robust JAK-STAT activation mechanism

DOI10.1016/j.jtbi.2012.04.031zbMath1411.92110OpenAlexW2128185895WikidataQ43861548 ScholiaQ43861548MaRDI QIDQ2632090

Mikołaj Rybiński, Anna Gambin

Publication date: 14 May 2019

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2012.04.031

zbMATH Keywords

robustnesssensitivity analysismodel selectionsignaling pathwayidentifiability analysis

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40)

Uses Software

• R
• SUNDIALS
• RankAggreg
• BioBayes
• BioModels
• SBML-SAT
• SOSlib
• PottersWheel

Cites Work

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• SUNDIALS
• Optimization by Simulated Annealing
• Thermodynamical approach to the travelling salesman problem: An efficient simulation algorithm
• Estimating the dimension of a model
• Robustness of the signal transduction system of the mammalian JAK/STAT pathway and dimerization steps
• On Profile Likelihood
• Bayes Factors
• Global sensitivity indices for nonlinear mathematical models and their Monte Carlo estimates
• A new look at the statistical model identification