Scratch assay microscopy: a reaction-diffusion equation approach for common instruments and data

DOI10.1016/j.mbs.2020.108482zbMath1460.92106OpenAlexW3090623941WikidataQ100431089 ScholiaQ100431089MaRDI QIDQ2657957

Elettra Sereni, Alessio Gnerucci, Paola Faraoni, Francesco Ranaldi

Publication date: 18 March 2021

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2020.108482

zbMATH Keywords

reaction-diffusion equationcell proliferationcell migrationscratch assaymicroscopy

Mathematics Subject Classification ID

Biomedical imaging and signal processing (92C55) Cell movement (chemotaxis, etc.) (92C17)

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Cites Work

• Reproducibility of scratch assays is affected by the initial degree of confluence: experiments, modelling and model selection
• Travelling waves in a wound healing assay.
• Multi-scale modeling of a wound-healing cell migration assay
• Hole-closing model reveals exponents for nonlinear degenerate diffusivity functions in cell biology
• Logistic proliferation of cells in scratch assays is delayed
• Using experimental data and information criteria to guide model selection for reaction-diffusion problems in mathematical biology
• Numerical Solution of Partial Differential Equations
• Some exact solutions of a generalized Fisher equation related to the problem of biological invasion

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