Time dependent asymptotic analysis of the gene regulatory network of the AcrAB-TolC efflux pump system in gram-negative bacteria

DOI10.1007/S00285-021-01576-4zbMath1460.92125OpenAlexW3135086474WikidataQ113905567 ScholiaQ113905567MaRDI QIDQ2661970

Laura J. V. Piddock, Sara Jabbari, Vito Ricci, Wang-Kan Xuan, George Youlden, John R. King

Publication date: 8 April 2021

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-021-01576-4

zbMATH Keywords

asymptotic analysismathematical modelling\textit{Escherichia coli}\textit{Salmonella}AcrAB-TolC

Mathematics Subject Classification ID

Systems biology, networks (92C42) Microbiology (92C70)

Related Items (1)

Mathematical modelling highlights the potential for genetic manipulation as an adjuvant to counter efflux-mediated MDR in \textit{Salmonella}

Cites Work

• Mathematical modelling of the agroperon in staphylococcus aureus
• Perturbation methods in applied mathematics
• A mathematical model of the P-glycoprotein pump as a mediator of multidrug resistance
• A mathematical model for the inhibition of the multidrug resistance- associated \(p\)-glycoprotein pump
• Mathematical modelling reveals properties of tcdc required for it to be a negative regulator of toxin production in \textit{clostridium difficile}

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