Escaping stochastic extinction of mutant virus: temporal pattern of emergence of drug resistance within a host

DOI10.1016/j.jtbi.2022.111029zbMath1483.92132OpenAlexW4206976641WikidataQ114182084 ScholiaQ114182084MaRDI QIDQ2670168

Yoh Iwasa, Rena Hayashi, Shingo Iwami

Publication date: 10 March 2022

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2022.111029

zbMATH Keywords

drug resistanceviral dynamicsescape mutanttime-dependent branching processes

Mathematics Subject Classification ID

Epidemiology (92D30) Applications of branching processes (60J85) Medical epidemiology (92C60)

Related Items (3)

Temporal pattern of the emergence of a mutant virus escaping cross-immunity and stochastic extinction within a host ⋮ Viral rebound occurrence immediately after drug discontinuation involving neither drug resistance nor latent reservoir ⋮ Waves of infection emerging from coupled social and epidemiological dynamics

Cites Work

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• Production of resistant HIV mutants during antiretroviral therapy
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