A fast and efficient approach for gene-based association studies of ordinal phenotypes

DOI10.1515/sagmb-2021-0068zbMath1504.62166OpenAlexW4318755795MaRDI QIDQ2683409

Qianran Wei, Nanxing Li, Yajing Zhou, Li Li Chen

Publication date: 10 February 2023

Published in: Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1515/sagmb-2021-0068

zbMATH Keywords

rare variantassociation analysisordinal phenotype

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10)

Uses Software

• SKAT
• ACAT

Cites Work

• Higher criticism for detecting sparse heterogeneous mixtures.
• Cauchy Combination Test: A Powerful Test With Analytic p-Value Calculation Under Arbitrary Dependency Structures
• Sequence Robust Association Test for Familial Data

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