An efficient strategy for identifying essential proteins based on homology, subcellular location and protein-protein interaction information

DOI10.3934/mbe.2022296OpenAlexW4225764936MaRDI QIDQ2686772

Bihai Zhao, Wei Yan, Meiping Jiang, Wang Zhang, Dong-Jie Wu, Yingchun Luo, Zhi-Hong Zhang

Publication date: 28 February 2023

Published in: Mathematical Biosciences and Engineering (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.3934/mbe.2022296

zbMATH Keywords

protein-protein interactionessential proteinhomology informationmultiple biological informationnon-negative matrix symmetric tri-factorizationsubcellular location information

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Cell biology (92C37) Systems biology, networks (92C42)

Uses Software

• UniProt

Cites Work

• SNFM: a semi-supervised NMF algorithm for detecting biological functional modules
• Data representation using robust nonnegative matrix factorization for edge computing
• Centers of complex networks

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