Modeling the interaction between \(\beta\)-amyloid aggregates and choline acetyltransferase activity and its relation with cholinergic dysfunction through two-enzyme/two-compartment model

DOI10.1155/2015/923762zbMath1335.92033OpenAlexW1700391494WikidataQ42094891 ScholiaQ42094891MaRDI QIDQ278122

Hedia Fgaier, Asmaa A. R. Awad, Ibrahim H. I. Mustafa, Ali Elkamel

Publication date: 2 May 2016

Published in: Computational \& Mathematical Methods in Medicine (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1155/2015/923762

zbMATH Keywords

\(\beta\)-amyloidcholine acetyltransferasepostsynaptic neuronpresynaptic neuron

Mathematics Subject Classification ID

Neural biology (92C20) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Cites Work

• A mathematical model of the impact of novel treatments on the A\(\beta\) burden in the Alzheimer's brain, CSF and plasma
• Complex bifurcation/chaotic behavior of acetylcholinesterase and cholineacetyltransferase enzymes system
• Chaotic behaviour of an acetylcholinesterase enzyme system

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