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Testing for Genetic Association in the Presence of Linkage and Gene-Covariate Interactions

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Publication:2786147
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DOI10.1002/bimj.200900057zbMath1207.62198OpenAlexW2015634691WikidataQ42259401 ScholiaQ42259401MaRDI QIDQ2786147

Jeremie J. Lebrec, Jeanine J. Houwing-Duistermaat, Andrea Callegaro

Publication date: 21 September 2010

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc3410551

zbMATH Keywords

score testgeneralized linear mixed modellinkagefamily-based association testsfamily-based studies


Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Generalized linear models (logistic models) (62J12) Medical applications (general) (92C50) Genetics and epigenetics (92D10)


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Hans van Houwelingen, 40 Years in Biostatistics



Cites Work

  • Testing Familial Aggregation
  • Approximate Inference in Generalized Linear Mixed Models
  • Testing the Fit of a Regression Model Via Score Tests in Random Effects Models
  • Score tests of genetic association in the presence of linkage based on the additive genetic gamma frailty model
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