Blinded sample size recalculation in multicentre trials with normally distributed outcome

DOI10.1002/BIMJ.200900114zbMath1205.62171OpenAlexW2057143066WikidataQ45995646 ScholiaQ45995646MaRDI QIDQ2786184

Katrin Jensen, Meinhard Kieser

Publication date: 21 September 2010

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.200900114

zbMATH Keywords

powernuisance parametervariance estimatetype I errorinternal pilot studysample size recalculationmulticentre clinical trial

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50)

Related Items (2)

Blinded and unblinded sample size reestimation procedures for stepped‐wedge cluster randomized trials ⋮ Blinded and unblinded sample size reestimation in crossover trials balanced for period

Cites Work

• Sample size re-estimation without unblinding for normally distributed outcomes with unknown variance
• Blinded sample size re-estimation with unequal variances and center effects in clinical trials
• Evaluation of Experiments with Adaptive Interim Analyses
• The design of multicentre trials
• Multicentre trials: a US regulatory perspective

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