Unbiased estimation of biomarker panel performance when combining training and testing data in a group sequential design

DOI10.1111/biom.12480zbMath1390.62312OpenAlexW2436232021WikidataQ31043044 ScholiaQ31043044MaRDI QIDQ2827204

Ziding Feng, Kim-Anh Do, Nabihah Tayob

Publication date: 12 October 2016

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc4974170

zbMATH Keywords

logistic regressiontwo-stage designsequential designconditional estimationbiomarker panelshrinkage correction

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Generalized linear models (logistic models) (62J12) Sequential statistical design (62L05)

Cites Work

• Asymptotic properties of the sequential empirical ROC, PPV and NPV curves under case-control sampling
• Overestimation of the receiver operating characteristic curve for logistic regression
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