Comparison of design strategies for a three-arm clinical trial with time-to-event endpoint: Power, time-to-analysis, and operational aspects

DOI10.1002/bimj.201500077zbMath1353.62115OpenAlexW2469874154WikidataQ47387422 ScholiaQ47387422MaRDI QIDQ2833466

Kaspar Rufibach, Jasmin Bahlo, Elina Asikanius, Gabriele Bieska, Hans Ulrich Burger

Publication date: 18 November 2016

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.201500077

zbMATH Keywords

multiplicityfamilywise error rateBonferroni correctionclosed hypothesis testinference strategylympocytic lymphomamultiarm clinical trial

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Paired and multiple comparisons; multiple testing (62J15)

Uses Software

• R

Cites Work

• Unnamed Item
• Testing a Primary and a Secondary Endpoint in a Group Sequential Design
• Monitoring Clinical Trials with Multiple Arms
• Literate Programming
• Discrete Sequential Boundaries for Clinical Trials
• On closed testing procedures with special reference to ordered analysis of variance
• Closed Testing Procedures for Group Sequential Clinical Trials with Multiple Endpoints
• Monitoring Pairwise Comparisons in Multi-Armed Clinical Trials
• Optimally weighted, fixed sequence and gatekeeper multiple testing procedures

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