Continual Reassessment Method for Partial Ordering
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Publication:2893418
DOI10.1111/j.1541-0420.2011.01560.xzbMath1274.62892OpenAlexW1976972195WikidataQ30423577 ScholiaQ30423577MaRDI QIDQ2893418
Nolan A. Wages, John O'Quigley, Mark Conaway
Publication date: 20 June 2012
Published in: Biometrics (Search for Journal in Brave)
Full work available at URL: http://europepmc.org/articles/pmc3141101
clinical trialpartial orderingdose-finding studiesmaximum tolerated dosecontinual reassessment methodtoxicitydrug combinationdose escalationphase 1 trials
Related Items (8)
Semiparametric Dose Finding Methods for Partially Ordered Drug Combinations ⋮ A novel framework to estimate multidimensional minimum effective doses using asymmetric posterior gain and \(\epsilon\)-tapering ⋮ Flexible use of copula‐type model for dose‐finding in drug combination clinical trials ⋮ Adaptive Bayesian phase I clinical trial designs for estimating the maximum tolerated doses for two drugs while fully utilizing all toxicity information ⋮ Evaluation of phase I clinical trial designs for combinational agents along with guidance based on simulation studies ⋮ Bayesian data augmentation dose finding with continual reassessment method and delayed toxicity ⋮ Adaptive clinical trial designs for phase I cancer studies ⋮ A Bayesian adaptive design in cancer phase I trials using dose combinations in the presence of a baseline covariate
Cites Work
- Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
- Confidence interval estimation subject to order restrictions
- Dose-Finding with Two Agents in Phase I Oncology Trials
- A Latent Contingency Table Approach to Dose Finding for Combinations of Two Agents
- Design and Analysis of Phase I Clinical Trials
- Designs for Single- or Multiple-Agent Phase I Trials
- Coherence principles in dose-finding studies
- Continual Reassessment Method: A Likelihood Approach
- A Parallel Phase I/II Clinical Trial Design for Combination Therapies
- Non-parametric optimal design in dose finding studies
- Two‐Dimensional Dose Finding in Discrete Dose Space
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