Optimal design for population pk/pd models

DOI10.2478/V10127-012-0012-1zbMath1313.62114OpenAlexW2076724474MaRDI QIDQ2913241

Alexander Aliev, Sergei L. Leonov

Publication date: 26 September 2012

Published in: Tatra Mountains Mathematical Publications (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.2478/v10127-012-0012-1

zbMATH Keywords

Fisher information matrixcompartmental models\(D\)-optimalityoptimal model-based designPK/PD models

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05)

Related Items (1)

Evaluation of the Fisher information matrix in nonlinear mixed effect models using adaptive Gaussian quadrature

Uses Software

• PkStaMp
• Monolix

Cites Work

• Unnamed Item
• Unnamed Item
• Unnamed Item
• Unnamed Item
• Unnamed Item
• Model-oriented design of experiments
• Sequences converging to D-optimal designs of experiments
• Further Developments of the Fisher Information Matrix in Nonlinear Mixed Effects Models with Evaluation in Population Pharmacokinetics
• PkStaMp Library for Constructing Optimal Population Designs for PK/PD Studies
• The Sequential Generation of $D$-Optimum Experimental Designs

This page was built for publication: Optimal design for population pk/pd models