Cooperative binding: a multiple personality

DOI10.1007/s00285-015-0922-zzbMath1347.82009OpenAlexW1258344798WikidataQ50567157 ScholiaQ50567157MaRDI QIDQ292669

Luis Diambra, Michael Habeck, Johannes W. R. Martini

Publication date: 8 June 2016

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-015-0922-z

zbMATH Keywords

binding curvescooperative bindingmacroscopic bindingmultiple personality

Mathematics Subject Classification ID

Chemistry (92E99) Biochemistry, molecular biology (92C40) Classical equilibrium statistical mechanics (general) (82B05) Biophysics (92C05) Lattice systems (Ising, dimer, Potts, etc.) and systems on graphs arising in equilibrium statistical mechanics (82B20)

Related Items (5)

A model for carrier-mediated biological signal transduction based on equilibrium ligand binding theory ⋮ On Hill coefficients and subunit interaction energies ⋮ Cooperativity, absolute interaction, and algebraic optimization ⋮ Decoupled molecules with binding polynomials of bidegree \((n,2)\) ⋮ A measure to quantify the degree of cooperativity in overall titration curves

Cites Work

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• A mathematical view on the decoupled sites representation
• A derivation of the grand canonical partition function for systems with a finite number of binding sites using a Markov chain model for the dynamics of single molecules
• Asymptotics of quantum relative entropy from a representation theoretical viewpoint

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