Heterogeneity in disease risk induces falling vaccine protection with rising disease incidence

DOI10.1080/14689367.2016.1187115zbMath1362.37164OpenAlexW2564309591MaRDI QIDQ2970387

M. Gabriela M. Gomes, Carlota Rebelo, Alessandro Margheri

Publication date: 30 March 2017

Published in: Dynamical Systems (Search for Journal in Brave)

Full work available at URL: https://archive.lstmed.ac.uk/6036/6/marego_3_15_PRevPscript.pdf

zbMATH Keywords

clinical trialsmathematical epidemiologyindividual heterogeneityvaccine efficacycohort selection

Mathematics Subject Classification ID

Epidemiology (92D30) Dynamical systems in biology (37N25)

Cites Work

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• Model hierarchies in edge-based compartmental modeling for infectious disease spread
• On the correlation between variance in individual susceptibilities and infection prevalence in populations
• Design and analysis of vaccine studies