Computational biology analysis of platelet signaling reveals roles of feedbacks through phospholipase C and inositol 1,4,5-trisphosphate 3-kinase in controlling amplitude and duration of calcium oscillations

DOI10.1016/j.mbs.2016.03.006zbMath1343.92189OpenAlexW2312117632WikidataQ50682686 ScholiaQ50682686MaRDI QIDQ299385

Fedor A. Balabin, Anastasia N. Sveshnikova

Publication date: 22 June 2016

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2016.03.006

zbMATH Keywords

positive feedbacknegative feedbackblood plateletcalcium signaling

Mathematics Subject Classification ID

Feedback control (93B52) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40) Computational methods for problems pertaining to biology (92-08) Biological rhythms and synchronization (92B25)

Uses Software

• COPASI

Cites Work

• A mathematical model of spontaneous calcium(II) oscillations in astrocytes
• Feedback Loops Shape Cellular Signals in Space and Time

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