Inference of directional selection and mutation parameters assuming equilibrium

DOI10.1016/j.tpb.2015.10.003zbMath1343.92325OpenAlexW2210694292WikidataQ40285225 ScholiaQ40285225MaRDI QIDQ304438

Claus Vogl, Juraj Bergman

Publication date: 25 August 2016

Published in: Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.tpb.2015.10.003

zbMATH Keywords

inferencebiallelic mutation-selection-drift modelequilibrium densitysmall scaled mutation rate

Mathematics Subject Classification ID

Problems related to evolution (92D15) Genetics and epigenetics (92D10)

Related Items (10)

Stationary distribution of a 2-island 2-allele wright-Fisher diffusion model with slow mutation and migration rates ⋮ An alternative derivation of the stationary distribution of the multivariate neutral Wright-Fisher model for low mutation rates with a view to mutation rate estimation from site frequency data ⋮ Maximum likelihood estimators for scaled mutation rates in an equilibrium mutation-drift model ⋮ The stationary distribution of a sample from the Wright-Fisher diffusion model with general small mutation rates ⋮ Inference in population genetics using forward and backward, discrete and continuous time processes ⋮ The transition distribution of a sample from a Wright-Fisher diffusion with general small mutation rates ⋮ An approximate stationary solution for multi-allele neutral diffusion with low mutation rates ⋮ Rate matrix estimation from site frequency data ⋮ A nearly-neutral biallelic Moran model with biased mutation and linear and quadratic selection ⋮ The stationary and quasi-stationary properties of neutral multi-type branching process diffusions

Uses Software

• R
• BayesDA

Cites Work

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• A coalescent dual process in a Moran model with genic selection
• Maximum likelihood and Bayesian methods for estimating the distribution of selective effects among classes of mutations using DNA polymorphism data
• A note on the sampling theory for infinite alleles and infinite sites models
• On the number of segregating sites in genetical models without recombination
• Ancestral processes with selection
• Genealogical processes for Fleming-Viot models with selection and recombination
• Development of neutral and nearly neutral theories
• The allele-frequency spectrum in a decoupled Moran model with mutation, drift, and directional selection, assuming small mutation rates
• Estimating the scaled mutation rate and mutation bias with site frequency data
• Diffusion models in population genetics
• Sufficiency of the number of segregating sites in the limit under finite-sites mutation

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