Adaptive dose-finding: Proof of concept with type I error control

DOI10.1002/bimj.200900222zbMath1201.62131OpenAlexW2113023722WikidataQ82060078 ScholiaQ82060078MaRDI QIDQ3056472

Frank Miller

Publication date: 12 November 2010

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.200900222

zbMATH Keywords

adaptive designdose-findingclinical studiesadaptive multiple contrast testconditional error approach

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical methods (62L99) Medical applications (general) (92C50)

Related Items (2)

Adaptive dose‐response studies to establish proof‐of‐concept in learning‐phase clinical trials ⋮ Dose response signal detection under model uncertainty

Uses Software

• MCPMod

Cites Work

• Unnamed Item
• Ordered tests in the analysis of variance
• Nonparametric Tests for Trend: Jonckheere's Test, a Modification and a Maximum Test
• Adaptive Sample Size Calculations in Group Sequential Trials
• Combining Multiple Comparisons and Modeling Techniques in Dose‐Response Studies

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