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Parameter estimation following an adaptive treatment selection trial design

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Publication:3076085
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DOI10.1002/bimj.200900134zbMath1208.62172OpenAlexW2035220329WikidataQ82871571 ScholiaQ82871571MaRDI QIDQ3076085

Xiaolong Luo, Samuel S. Wu, Jie Xiong

Publication date: 17 February 2011

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.200900134


zbMATH Keywords

adaptive designbinomialRao-Blackwellphase II clinical trialdose selection


Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Design of statistical experiments (62K99) Estimation in survival analysis and censored data (62N02)




Cites Work

  • Drop-the-losers design: binomial case
  • Two stage conditionally unbiased estimators of the selected mean
  • Point estimates and confidence regions for sequential trials involving selection
  • Unbiased estimation of the parameter of a selected binomial population
  • A Two-Stage Design for Choosing among Several Experimental Treatments and a Control in Clinical Trials
  • Estimation of the mean of the selected population




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