Monitoring Clinical Trials with Multiple Arms

DOI10.1111/j.0006-341X.2001.00892.xzbMath1209.62187OpenAlexW2020373362WikidataQ74497647 ScholiaQ74497647MaRDI QIDQ3078836

Martin Hellmich

Publication date: 1 March 2011

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1111/j.0006-341x.2001.00892.x

zbMATH Keywords

multiple testingclosed testingmultiple treatmentsadaptive interim analysisgroup sequential trials

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical analysis (62L10)

Related Items

Sample size re-estimation for confirmatory two-stage flexible multi-arm trial with normal outcomes ⋮ Statistical monitoring of clinical trials with multivariate response and/or multiple arms: a flexible approach ⋮ Sequential Methods in Multi-Arm Clinical Trials ⋮ Bayesian Incentive-Compatible Bandit Exploration ⋮ Comparison of design strategies for a three-arm clinical trial with time-to-event endpoint: Power, time-to-analysis, and operational aspects

Uses Software

• R

Cites Work

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• A Group Sequential Procedure for All-Pairwise Comparisons of k Treatments Based on the Range Statistic
• Closed Testing Procedures for Group Sequential Clinical Trials with Multiple Endpoints
• Adaptive Sample Size Calculations in Group Sequential Trials
• Monitoring Pairwise Comparisons in Multi-Armed Clinical Trials
• Evaluation of Experiments with Adaptive Interim Analyses