Seamlessly Expanding a Randomized Phase II Trial to Phase III

DOI10.1111/j.0006-341X.2002.00823.xzbMath1210.62168WikidataQ52025987 ScholiaQ52025987MaRDI QIDQ3079028

Donald A. Berry, Peter F. Thall, Lurdes Y. T. Inoue

Publication date: 1 March 2011

Published in: Biometrics (Search for Journal in Brave)

zbMATH Keywords

Markov chain Monte Carloclinical trialsmixture modelsBayesian sequential design

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Bayesian inference (62F15) Medical applications (general) (92C50) Sequential statistical design (62L05)

Related Items

SEAMLESS PHASE II/III CLINICAL TRIALS WITH COVARIATE ADAPTIVE RANDOMIZATION, Methodology and application of adaptive and sequential approaches in contemporary clinical trials, Bayesian group sequential enrichment designs based on adaptive regression of response and survival time on baseline biomarkers, Bayesian statistics and the efficiency and ethics of clinical trials, A Parallel Phase I/II Clinical Trial Design for Combination Therapies, A review of phase 2-3 clinical trial designs, Discussion on “A Hybrid Selection and Testing Procedure with Curtailment for Comparative Clinical Trials” by Elena M. Buzaianu and Pinyuen Chen

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