Choice of Number of Doses for Maximum Likelihood Estimation of the ED50 for Quantal Dose-Response Data

DOI10.2307/2531635zbMath0715.62255OpenAlexW2314837765WikidataQ34626163 ScholiaQ34626163MaRDI QIDQ3201562

Thomas Schmitt, Hans-Georg Müller

Publication date: 1990

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.2307/2531635

zbMATH Keywords

information matrixmaximum likelihood methodbioassayasymptotic mean squared errormedian effective doseED50allocation of dosesdesign densitiessymmetric dose- response curve

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05) Point estimation (62F10)

Related Items (4)

Robust designs for dose-response studies: model and labelling robustness ⋮ A two-stage hybrid procedure for estimating an inverse regression function ⋮ Robustness of interval estimation of the 90% effective dose: Bootstrap resampling and some large-sample parametric methods ⋮ Selection of number of dose levels and its robustness for binary response data

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