High-Dimensional ODEs Coupled With Mixed-Effects Modeling Techniques for Dynamic Gene Regulatory Network Identification

DOI10.1198/jasa.2011.ap10194zbMath1234.62146OpenAlexW2025825535WikidataQ41813504 ScholiaQ41813504MaRDI QIDQ3225789

Hulin Wu, Hongzhe Li, Hua Liang, Tao Lü

Publication date: 22 March 2012

Published in: Journal of the American Statistical Association (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc3509540

zbMATH Keywords

differential equations smoothly clipped absolute deviation network graph stochastic approximation EM Saccharomyces cerevisiae time course microarray data nonparametric mixed effects two-stage smoothing-based method yeast cell cycles

Mathematics Subject Classification ID

Classification and discrimination; cluster analysis (statistical aspects) (62H30) Applications of statistics to biology and medical sciences; meta analysis (62P10) Applications of graph theory (05C90) Monte Carlo methods (65C05) Dynamical systems in biology (37N25) Biochemistry, molecular biology (92C40) Stochastic approximation (62L20) Systems biology, networks (92C42)

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