Mathematical modeling and systems pharmacology of tuberculosis: isoniazid as a case study

DOI10.1016/J.JTBI.2016.03.038zbMath1347.92031OpenAlexW2327834446WikidataQ40722388 ScholiaQ40722388MaRDI QIDQ327196

Laure Lalande, Laurent Bourguignon, Pascal Maire, Sylvain Goutelle

Publication date: 19 October 2016

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2016.03.038

zbMATH Keywords

pharmacokineticspharmacodynamicsimmune response\textit{Mycobacterium tuberculosis}antimycobacterial drugs

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical epidemiology (92C60)

Uses Software

• GUI-HDMR

Cites Work

• Mathematical modeling of pulmonary tuberculosis therapy: insights from a prototype model with rifampin
• The human immune response to \textit{Mycobacterium tuberculosis} in lung and lymph node
• A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment

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