Topics in mathematical pharmacology

DOI10.1007/s10884-015-9468-4zbMath1350.92029OpenAlexW947716554WikidataQ59474526 ScholiaQ59474526MaRDI QIDQ330557

Lambertus A. Peletier, Neil Benson, Piet H. van der Graaf

Publication date: 26 October 2016

Published in: Journal of Dynamics and Differential Equations (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s10884-015-9468-4

zbMATH Keywords

TMDDdrug-dispositionmodular systemsRTK'ssignalling

Mathematics Subject Classification ID

Medical applications (general) (92C50) Biochemistry, molecular biology (92C40)

Related Items (6)

Asymptotic analysis of a target-mediated drug disposition model: algorithmic and traditional approaches ⋮ Insights into the dynamics of ligand-induced dimerisation via mathematical modelling and analysis ⋮ Asymptotic analysis of a TMDD model: when a reaction contributes to the destruction of its product ⋮ Optimization of additive chemotherapy combinations for an in vitro cell cycle model with constant drug exposures ⋮ Geometric singular perturbation analysis of a dynamical target mediated drug disposition model ⋮ Analytical solution and exposure analysis of a pharmacokinetic model with simultaneous elimination pathways and endogenous production: the case of multiple dosing administration

Cites Work

• Mathematical analysis of the pharmacokinetic-pharmacodynamic (PKPD) behaviour of monoclonal antibodies: predicting \textit{in vivo} potency
• Cross-membrane signal transduction of receptor tyrosine kinases (RTKs): from systems biology to systems pharmacology
• A mathematical analysis of rebound in a target-mediated drug disposition model. I: Without feedback

This page was built for publication: Topics in mathematical pharmacology