On high-dimensional misspecified mixed model analysis in genome-wide association study

DOI10.1214/15-AOS1421zbMath1358.62095MaRDI QIDQ342680

Debashis Paul, Can Yang, Cong Li, Hongyu Zhao, Jiming Jiang

Publication date: 18 November 2016

Published in: The Annals of Statistics (Search for Journal in Brave)

zbMATH Keywords

heritabilityvariance componentsrandom matrix theoryestimatorasymptotic propertygenetic implicationsmisspecified linear mixed model (LMM)MMMArestricted maximum likelihood (REML)

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Point estimation (62F10) Random matrices (probabilistic aspects) (60B20) General nonlinear regression (62J02) Protein sequences, DNA sequences (92D20)

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