Multiscale modelling of intestinal crypt organization and carcinogenesis

DOI10.1142/S0218202515400187zbMath1346.92032arXiv1506.05019MaRDI QIDQ3451242

Alexander G. Fletcher, Philip K. Maini, Philip J. Murray

Publication date: 10 November 2015

Published in: Mathematical Models and Methods in Applied Sciences (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1506.05019

zbMATH Keywords

multiscale modelscontinuum modelscolorectal cancercoarse-grainingintestineoff-lattice models

Mathematics Subject Classification ID

Medical applications (general) (92C50)

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Cites Work

• A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt
• A convection-diffusion-shape model for aberrant colonic crypt morphogenesis
• Modelling the role of the basement membrane beneath a growing epithelial monolayer
• Mathematical modeling of monoclonal conversion in the colonic crypt
• Individual-based models to growth and folding in one-layered tissues: intestinal crypts and early development.
• Assessing first-order emulator inference for physical parameters in nonlinear mechanistic models
• A review of spatial computational models for multi-cellular systems, with regard to intestinal crypts and colorectal cancer development
• A hybrid approach to multi-scale modelling of cancer
• Lattice-Gas Cellular Automaton Modeling of Emergent Behavior in Interacting Cell Populations
• Continuum approximations of individual-based models for epithelial monolayers

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