Derivation of Exact Distributions Following an Up-and-Down Design

DOI10.1080/03610920902947709zbMath1175.62014OpenAlexW1969234538MaRDI QIDQ3645036

Mario Stylianou

Publication date: 16 November 2009

Published in: Communications in Statistics - Theory and Methods (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/03610920902947709

zbMATH Keywords

exact distributiontoxicityphase I trialdose findingbiased coin up-and-down design

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Exact distribution theory in statistics (62E15) Sequential statistical design (62L05)

Related Items (1)

Adaptive clinical trial designs for phase I cancer studies

Cites Work

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• Dose Finding Using the Biased Coin Up-and-Down Design and Isotonic Regression
• A Random Walk Rule for Phase I Clinical Trials
• Toxicity in sequential dose-response experiments

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