The Search for Optimality in Clinical Trials

DOI10.2307/1402871zbMath0586.62129OpenAlexW1986376095MaRDI QIDQ3711548

Peter Armitage

Publication date: 1985

Published in: International Statistical Review / Revue Internationale de Statistique (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.2307/1402871

zbMATH Keywords

randomizationhorizonclinical trialsethicsphase II trialsadaptive allocationplay the winneradaptive sequential methodsdata-dependent allocationdecision theoretic methods

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05) Sequential statistical analysis (62L10)

Related Items (21)

SEQUENTIAL METHODS IN CLINICAL TRIALS* ⋮ Generalisations of a Bayesian decision-theoretic randomisation procedure and the impact of delayed responses ⋮ A repeated significance test in a linear model ⋮ Sequential allocation in clinical trials ⋮ Some topics of current interest in clinical trials ⋮ The Teaching of Statistics in the Biological, Medical and Health Sciences: Some Comments and a Selected Bibliography ⋮ Bayesian bandits in clinical trials ⋮ Sequential procedures for comparing several medical treatments ⋮ Response-adaptive randomization in clinical trials: from myths to practical considerations ⋮ GROUP SEQUENTIAL TESTS WITH OUTCOME-DEPENDENT TREATMENT ASSIGNMENT ⋮ Truncated sequential medical trials involving paired data ⋮ Herbert Robbins and sequential analysis ⋮ A program for sequential allocation of three Bernoulli populations ⋮ A random horizon model for sequential clinical trials ⋮ Optimal Bayesian adaptive trials when treatment efficacy depends on biomarkers ⋮ Using randomization tests to preserve type I error with response adaptive and covariate adaptive randomization ⋮ Ethics, data-dependent designs, and the strategy of clinical trials: time to start learning-as-we-go? ⋮ Statistical Inference for Online Decision Making: In a Contextual Bandit Setting ⋮ Optimal few-stage designs ⋮ Analysis of homogeneity of treatment effect in adaptive multicenter clinical trials ⋮ Multi-armed bandit models for the optimal design of clinical trials: benefits and challenges

This page was built for publication: The Search for Optimality in Clinical Trials