Dimensionality reduction of bistable biological systems

DOI10.1007/s11538-013-9807-8zbMath1308.92042OpenAlexW2028318107WikidataQ51261895 ScholiaQ51261895MaRDI QIDQ376424

Mohammad Hasan, H. S. Yoon

Publication date: 5 November 2013

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-013-9807-8

zbMATH Keywords

canonical correlation analysissimilarity transformationdimensionality reductionbistabilitytime-scales hierarchy

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

Uses Software

• crntwin
• Optknock

Cites Work

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• Model decomposition and reduction tools for large-scale networks in systems biology
• Relations among \(m\) sets of measures
• On the validity of the steady state assumption of enzyme kinetics
• Model reduction by extended quasi-steady-state approximation
• The Quasi-Steady-State Assumption: A Case Study in Perturbation
• Understanding bistability in complex enzyme-driven reaction networks

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