Predictive Probability Early Termination Plans For Phase II Clinical Trials

DOI10.2307/2530109zbMath0423.62056OpenAlexW2320759023WikidataQ41032503 ScholiaQ41032503MaRDI QIDQ3857600

Jay Herson

Publication date: 1979

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.2307/2530109

zbMATH Keywords

powersizeclinical trialsaverage sample sizepredictive probability early termination plans

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Bayesian problems; characterization of Bayes procedures (62C10) Sequential statistical design (62L05)

Related Items (6)

CONDITIONAL PROBABILITY OF SIGNIFICANCE FOR EARLY STOPPING IN FAVOR OFH₀ ⋮ Data monitoring in complex clinical trials: Which treatment is better? ⋮ SEQUENTIAL METHODS IN CLINICAL TRIALS* ⋮ Power calculations for replication studies ⋮ Optimal and lead-in adaptive allocation for binary outcomes: A comparison of Bayesian methods ⋮ A hybrid Bayesian-frequentist predictive design for monitoring multi-stage clinical trials

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