Information in a two-stage adaptive optimal design

DOI10.1016/J.JSPI.2013.07.010zbMath1432.62246OpenAlexW2048547502MaRDI QIDQ389442

Adam Lane, Ping Yao, Nancy Flournoy

Publication date: 20 January 2014

Published in: Journal of Statistical Planning and Inference (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jspi.2013.07.010

zbMATH Keywords

bioassaysFisher informationexperimental designsoptimal designsdose-findingobserved informationphase Iresponse-adaptive design

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05) General nonlinear regression (62J02) Sequential statistical design (62L05)

Related Items (9)

The effects of adaptation on maximum likelihood inference for nonlinear models with normal errors ⋮ Conditional Estimation in Two-Stage Adaptive Designs ⋮ Optimal subsampling for softmax regression ⋮ Two-stage adaptive optimal design with fixed first-stage sample size ⋮ Convergence of least squares estimators in the adaptive Wynn algorithm for some classes of nonlinear regression models ⋮ Random norming AIDS analysis of non-linear regression models with sequential informative dose selection ⋮ Inference for a two-stage enrichment design ⋮ Efficiency of observed information adaptive designs in linear models ⋮ A conversation with Nancy Flournoy

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