Incorporation of a stopping criterion for futility into the design of a clinical trial with one interim analysis

DOI10.1080/03610929708831964zbMath0917.62070OpenAlexW1981748695MaRDI QIDQ4226911

Nedjad Losic, U. Strömberg, Jan Lanke

Publication date: 23 February 1999

Published in: Communications in Statistics - Theory and Methods (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/03610929708831964

zbMATH Keywords

group sequential designconditional powerstochastic curtailment

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05)

Cites Work

• Group sequential designs for one-sided and two-sided hypothesis testing with provision for early stopping in favor of the null hypothesis
• Statistical approaches to interim monitoring of medical trials: A review and commentary
• Stochastically curtailed tests in long–term clinical trials
• Two-Stage Experimental Designs: Early Stopping with a Negative Result

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