Adjusting for Differential Rates of Prophylaxis Therapy for PCP in High-Versus Low-Dose AZT Treatment Arms in an AIDS Randomized Trial

DOI10.2307/2290899zbMath0806.92010OpenAlexW4230649572MaRDI QIDQ4314944

Sander Greenland, James M. Robins

Publication date: 16 February 1995

Full work available at URL: https://doi.org/10.2307/2290899

zbMATH Keywords

survival analysissemiparametric modelstime-dependent covariatesdependent censoringcausal inferenceintermediate variablesdirect effectsacquired immunodeficiency syndromestructural nested failure time modelssurrogate markersrandomized trialsG-estimationG-computation algorithmmedian survival3-azido- 3-deoxythymidineAIDS clinical trial groupcounterfactual variableshigh- dose AZT armlow-dose AZTnon-random non-compliancepneumocystis carinii pseumoniaprophylaxis therapy

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50)

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