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A note on the robustness of the continual reassessment method

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Publication:433569
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DOI10.1016/J.SPL.2012.01.026zbMath1321.62105OpenAlexW2047996681MaRDI QIDQ433569

David Azriel

Publication date: 5 July 2012

Published in: Statistics \& Probability Letters (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.spl.2012.01.026


zbMATH Keywords

consistencymisspecified modelcontinual reassessment methodphase I trials


Mathematics Subject Classification ID

Nonparametric robustness (62G35) Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05)


Related Items (4)

Optimal sequential designs in phase I studies ⋮ Information in a two-stage adaptive optimal design ⋮ Adaptive clinical trial designs for phase I cancer studies ⋮ A conversation with Nancy Flournoy




Cites Work

  • Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
  • The treatment versus experimentation dilemma in dose finding studies
  • A Simple Technique to Evaluate Model Sensitivity in the Continual Reassessment Method
  • Consistency of continual reassessment method under model misspecification




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