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Estimating and reducing bias in group sequential designs with Gaussian independent increment structure

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Publication:4376595
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DOI10.1093/biomet/84.4.831zbMath0892.62059OpenAlexW1989152006MaRDI QIDQ4376595

David L. Demets, José C. Pinheiro

Publication date: 11 February 1998

Published in: Biometrika (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/biomet/84.4.831


zbMATH Keywords

clinical trialsgroup sequential testalpha-spending method


Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05) Sequential statistical analysis (62L10)


Related Items (2)

An overview of group sequential methods in longitudinal clinical trials ⋮ Point estimation after early stopping in a repeated measures trial






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