Change-point model on nonhomogeneous Poisson processes with application in copy number profiling by next-generation DNA sequencing

DOI10.1214/11-AOAS517zbMath1243.62112arXiv1206.6627MaRDI QIDQ439133

Jeremy J. Shen, Nancy R. Zhang

Publication date: 1 August 2012

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1206.6627

zbMATH Keywords

change pointCNVpoint-wise confidence intervals

Mathematics Subject Classification ID

Parametric tolerance and confidence regions (62F25) Applications of statistics to biology and medical sciences; meta analysis (62P10) Non-Markovian processes: estimation (62M09) Bayesian inference (62F15) Markov processes: estimation; hidden Markov models (62M05) Biochemistry, molecular biology (92C40)

Related Items (6)

Scan statistics on Poisson random fields with applications in genomics ⋮ Detecting abrupt changes in the spectra of high-energy astrophysical sources ⋮ Approximations of distributions of scan statistics of inhomogeneous Poisson processes ⋮ Minimax and adaptive tests for detecting abrupt and possibly transitory changes in a Poisson process ⋮ Asymptotics for change-point models under varying degrees of mis-specification ⋮ Nonparametric intensity estimation from noisy observations of a Poisson process under unknown error distribution

Uses Software

• clue
• seqCBS
• CNV-seq

Cites Work

• Unnamed Item
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• Stochastic segmentation models for array-based comparative genomic hybridization data analysis
• The problem of the Nile: Conditional solution to a changepoint problem
• Confidence Sets in Change-Point Problems
• Circular binary segmentation for the analysis of array-based DNA copy number data
• A method for calling gains and losses in array CGH data
• A Modified Bayes Information Criterion with Applications to the Analysis of Comparative Genomic Hybridization Data
• Inference about the change-point in a sequence of random variables
• Research in Computational Molecular Biology

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