THE DISTRIBUTION OF THE MAXIMUM LIKELIHOOD ESTIMATOR IN UP-AND-DOWN EXPERIMENTS FOR QUANTAL DOSE-RESPONSE DATA

DOI10.1081/BIP-100101190zbMath0961.62104WikidataQ30581166 ScholiaQ30581166MaRDI QIDQ4512637

Rolf Sundberg, Mårten Vågerö

Publication date: 3 December 2000

Published in: Journal of Biopharmaceutical Statistics (Search for Journal in Brave)

zbMATH Keywords

logistic regressionbiassimulation studiesstaircase methodED50Markov chain representationtolerance threshold distribution

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05)

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Cites Work

• On second-order optimality of the observed Fisher information
• Asymptotic Properties of the Block Up-and-Down Method in Bio-assay
• A Method for Obtaining and Analyzing Sensitivity Data
• The Up-and-Down Method with Small Samples