Sequential Monitoring of Covariate-Adaptive Randomized Clinical Trials

DOI10.5705/SS.202016.0330zbMath1412.62191OpenAlexW2736290861MaRDI QIDQ4626689

Hongjian Zhu, Fei-fang Hu

Publication date: 28 February 2019

Published in: Statistica Sinica (Search for Journal in Brave)

Full work available at URL: https://semanticscholar.org/paper/a38a123b59b46c11072c81d24f9a55218c17aad0

zbMATH Keywords

Brownian motionlinear regressionpersonalized medicinetype I error ratesequential monitoringPocock-Simon's randomizationstratified permuted block randomization

Mathematics Subject Classification ID

Linear regression; mixed models (62J05) Applications of statistics to biology and medical sciences; meta analysis (62P10) Brownian motion (60J65) Sequential estimation (62L12)

Related Items (4)

Comment on ‘Inference after covariate-adaptive randomisation: aspects of methodology and theory’ ⋮ Rejoinder on ‘Inference after covariate-adaptive randomization: aspects of methodology and theory’ ⋮ SEAMLESS PHASE II/III CLINICAL TRIALS WITH COVARIATE ADAPTIVE RANDOMIZATION ⋮ Multi-arm covariate-adaptive randomization

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